13) Zhu, G., Myint, M., Ang, W. H., Lina, S. and Lippard, S. J. (2011) Monofunctional platinum-DNA adducts are strong inhibitors of transcription and substrates for nucleotide excision repair in live mammalian cells. Cancer Res. Published OnlineFirst December 16, 2011; doi:10.1158/0008-5472.CAN-11-3151

12) Daghestani, H. N., Zhu, G., Johnston, P. A., Shinde, S. N., Brodsky, J. L., Vallee, R. B., and Day, B. W. (2011) Characterization of Inhibitors of Glucocorticoid Receptor Nuclear Translocation: A Model of Cytoplasmic Dynein-mediated Cargo Transport. Assay Drug Dev. Technol. Online Ahead of Print; doi:10.1089/adt.2010.0367

11) Graf, N., Ang, W. H., Zhu, G., Myint, M., and Lippard, S. J. (2011) Role of endonucleases XPF and XPG in nucleotide excision repair of platinated DNA and cisplatin/oxaliplatin cytotoxicity in osteosarcoma cells. ChemBioChem 12, 1115-1123

10) Zhu, G., Chang, P., and Lippard, S. J. (2010) Recognition of platinum damage by poly(ADP-ribose) polymerase. Biochemistry 49, 6177–6183

9) Wang, D., Zhu, G., Huang, X. and Lippard, S. J. (2010) Structural basis of RNA polymerase II transcription inhibition by pyriplatin, a monofunctional anticancer agent. Proc. Natl. Acad. Sci. U.S.A. 107, 9584-9589
[Highlighted in Faculty of 1000 Biology: http://f1000biology.com/article/id/4041963/evaluation; SSRL Science Highlight - January 2011]

8) Vogt, A., McPherson, P. A., Shen, X., Balachandran, R., Zhu, G., Raccor, B. S., Nelson, S. G., Tsang, M., and Day, B. W. (2009) High-content analysis of cancer-cell-specific apoptosis and inhibition of in vivo angiogenesis by synthetic (-)-pironetin and analogs. Chem. Biol. Drug Des. 74, 358-368

7) Zhu, G., and Lippard, S. J. (2009) Photoaffinity labeling reveals nuclear proteins that uniquely recognize cisplatin-DNA interstrand cross-links. Biochemistry 48, 4916-4925
[News story describing this work was highlighted in Rouzer, C. A. (2009) Chem. Res. Toxicol. 22, 1215-1216]

6) Wright, C. M., Chovatiya, R. J., Jameson, N. E., Turner, D. M., Zhu, G., Werner, S., Huryn, D. M., Pipas, J. M., Day, B. W., Wipf, P., and Brodsky, J. L. (2008) Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation. Bioorg. Med. Chem. 16, 3291-3301

5) Wang, Z., McPherson, P. A., Raccor, B. S., Balachandran, R., Zhu, G., Day, B. W., Vogt, A., and Wipf, P. (2007) Structure-activity and high-content imaging analyses of novel tubulysins. Chem. Biol. Drug Des. 70, 75-86

4) Zhu, G., Yang, F., Balachandran, R., Höök, P., Vallee, R. B., Curran, D. P., and Day, B. W. (2006) Synthesis and biological evaluation of purealin and analogues as cytoplasmic dynein heavy chain inhibitors. J. Med. Chem. 49, 2063-2076

3) Madiraju, C., Edler, M. C., Hamel, E., Raccor, B. S., Balachandran, R., Zhu, G., Giuliano, K. A., Vogt, A., Shin, Y., Fournier, J. H., Fukui, Y., Bruckner, A. M., Curran, D. P., and Day, B. W. (2005) Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin. Biochemistry 44, 15053-15063

2) Shin, Y., Fournier, J. H., Balachandran, R., Madiraju, C., Raccor, B. S., Zhu, G., Edler, M. C., Hamel, E., Day, B. W., and Curran, D. P. (2005) Synthesis and biological evaluation of (-)-16-normethyldictyostatin: a potent analogue of (-)-dictyostatin. Org. Lett. 7, 2873-2876

1) Janjic, J. M., Mu, Y., Kendall, C., Stephenson, C. R., Balachandran, R., Raccor, B. S., Lu, Y., Zhu, G., Xie, W., Wipf, P., and Day, B. W. (2005) New antiestrogens from a library screen of homoallylic amides, allylic amides, and C-cyclopropylalkylamides. Bioorg. Med. Chem. 13, 157-164