Output

Publications at CityU

(* denotes corresponding author. † denotes equal contribution.)

  1. W. Zheng, T. J. H. Chang, X. Li, Z. Zhou, C. Tin, K. Vong, P. Karam, P. K. Lo.* “Membrane Fusion-Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple-Negative Breast Cancer” Advanced Science 2026, e76100.

  2. M. P. Ng, W. X. Toh, X. Li, P. K. Lo, W. K. Tang, W. C. Chan, S. H. Lim, M. F. Khyasudeen, W. Liu, H. Xiao, K. Shang, C. H. Tan, C. W. Ang, K. S. Sim, K. W. Tan “A Mitochondria-Targeting Organotin(IV) Bifunctional Scaffold for Colorectal Carcinoma” European Journal of Inorganic Chemistry, 2026, e70273.

  3. J. Huang, Y. Li, P. K. Lo, K. Vong. “Development of Palladium-Based Multivalent Lectin-Direct Artificial Metalloenzymes” Bioorg. Med. Chem., 2026, 136, 118603.

  4. Z. Luo, X. Bian, B. Peng, J. Chen, P. K. Lo,* L. Zhou,* Y. Wen.* “Engineered Bionanomaterials For Precision Delivery of Nucleic Acid Drugs” Small, 2025, 21, e02667.

  5. Z. Zhuo†, H. Y. Chan†, P. K. Lo*. “Precision Control of Light-Responsive Nucleic Acids Modified With Photoremovable Protecting Groups for Functionalization” JACS Au, 2025, 5, 7, 2953-2976.

  6. H. M. Leung†, H. Y. Chan†, M. Klimezak, L.S. Liu, P. Karam, A. Specht,* F. Bolze,* P. K. Lo.* “Robust Photocleavable Linkers for DNA Synthesis: Enabling Visible Light-Triggered Antisense Oligonucleotide Release in 3D DNA Nanocages” Biomacromolecules, 2025, 26, 5, 3113–3127.

  7. C. O. K. Law†, H. M. Leung†, M. Wang†, Q. Nie, Q. H. Pham, K. C. Han, T. S. Wong, K. T. Chow,* P. K. Lo,* T. C. K. Lau.* “Harnessing Intracellular Bacteria in Bladder By Intravesical Delivery of Antibiotics-Loaded Nanodiamonds to Reduce the Recurrence of Urinary Tract Infection” Journal of Nanobiotechnology, 2025, 23, 367.

  8. S. Y. Lam†, P. Li†, L. Jin, H. Y. Chan, Y. Ruan, C. K. Kwok,* P. K. Lo.* “Enhanced Detection of Enrofloxacin in Seawater Using a Newly Selected Aptamer on a Graphite Oxide-Based Biosensor” Analytical Chemistry, 2025, 97, 12, 6735-6744.

  9. C. H. Lau, K. Guo, G. Chen, Z. Zhou, T. Wang, Z. Huang, J. Li, W. Dong, Y. Huang, P. K. Lo, H. Xue, X. Huang, C. Tin, H. Zhu. “Artificial Base Mismatches-Mediated PCR (ABM-PCR) for Detecting Clinically relevant single-base mutations” Clinical Chemistry and Laboratory Medicine, 2025, 63, 7, 1301-1314.

  10. D. Y. Tam†, P. Li†, L. S. Liu, F. Wang, H. M. Leung, P. K. Lo.* “Versatility of Threose Nucleic Acids: Synthesis, Properties, and Applications in Chemical Biology and Biomedical Advancements” Chem. Commun. 2024, 60, 11864 - 11889.

  11. P. Li, S. Zheng, H. M. Leung, L. S. Liu, T. J. H. Chang, A. Maryam, F. Wang *, Y. R. Chin,* P. K. Lo.* “TNA-Mediated Antisense Strategy To Knockdown Akt Genes For Triple-Negative Breast Cancer Therapy” Small Methods 2024, 2400291.

  12. H. M. Leung, L. S. Liu, Y. Cai, X. Li, Y. Huang, H. C. Chu, Y R. Chin, P. K. Lo.* “Light-Activated Nanodiamond-Based Drug Delivery Systems For Spatiotemporal Release of Antisense Oligonucleotides” Bioconjugate Chem. 2024, 35, 5, 623-632.

  13. P. Li, C. Zhu, L. S. Liu, T. J. H. Chang, H. C. Chu, Z. Li, Z. Mao, F. Wang, P. K. Lo.* “Ultra-Stable Threose Nucleic Acid-Based Biosensors For Rapid And Sensitive Nucleic Acid Detection And In Vivo Imaging” Acta Biomaterialia, 2024, 177, 15, 472-485.

  14. L. S. Liu, H. M. Leung, Y. Cai, P. K. Lo.* “Recent Progress in Stimuli-Responsive DNA-Based Logic Gates: Design, Working Principles And Biological Applications”, Smart Molecules 2024, 2, 1, e20230023.

  15. P. K. Lo.* “Nanometre-Scale Biosensors Revolutionizing Applications in Biomedical and Environmental Research” Biosensors 2023, 13, 11, 969.

  16. Z. Zhu, H. Lu, L. Jin, Y. Gao, Z. Qian, W. Tong,* P. K. Lo,* Z. Mao,* H.Shi.* “C-176 Loaded Ce DNase Nanoparticles Synergistically Inhibit The cGAS-STING Pathway for Ischemic Stroke Treatment” Bioactive Materials 2023, 18, 29, 230-240.

  17. X. Jiang, J., Zhang; P. K. Lo,* Z. Mao.* “Polyphenol-Based Assembly Nanosystems as Multifunctional Biopharmaceutical Platform” Adv. NanoBiomed Res.2023, 3, 6, 2200168.

  18. H. M. Leung, H. C. Chu, Z. Mao, P. K. Lo.* “Versatile Nanodiamond-Based Tools for Therapeutics and Bioimaging” Chem. Commun. 2023, 59, 15, 2039-2055.

  19. L. S. Liu, H. M. Leung, C. Morville; H. C. Chu, J. Y. Tee, A. Specht*, F. Bolze*, P. K. Lo.* “Wavelength-Dependent, Orthogonal Photoregulation of DNA Liberation for Logic Operations” ACS Applied Materials & Interfaces 2023, 15, 1, 1944–1957.

  20. F. Wang, L. S. Liu, P. Li, C. H. Lau, H. M. Leung, Y R. Chin, C. Tin, P. K. Lo.* “Cellular Uptake, Tissue Penetration, Biodistribution, and Biosafety of Threose Nucleic Acids: Assessing In Vitro and In Vivo Delivery” Materials Today Bio 2022, 18, 15, 100299.

  21. F. Wang, P. Li, H. C. Chu, P. K. Lo.* “Nucleic Acids and Their Analogues for Biomedical Applications” Biosensors 2022, 12, 2, 93.

  22. F. Wang, L. S. Liu, P. Li, H. M. Leung, D. Y. Tam, P. K. Lo.* “Biologically Stable Threose Nucleic Acid-Based Probes for Real-Time microRNA Detection and Imaging in Living Cells” Molecular Therapy - Nucleic Acids 2022, 3, 27, 787-796.

  23. F. Wang†, X. Men†, Ha. Chen, F.Mi, M. Xu, X. Men, Z. Yuan,* P. K. Lo.* “Second Near Infrared Photoactivatable Biocompatible Polymer Nanoparticles for Effective in Vitro and in Vivo Cancer Theranostics” Nanoscale, 2021, 13, 31, 13410-13420.

  24. H. M. Leung, C. H. Lau, J. W. -T. Ho, M. S. Chan, T. J. H. Chang, L. H. Law, F. Wang D. Y. Tam, L. S. Liu, K. W. Y. Chan, C. Tin,* P. K. Lo.* “Targeted Brain Tumor Imaging by Using Discrete Biopolymer-Coated Nanodiamonds across the Blood Brain Barrier” Nanoscale, 2021, 13, 5, 3184 – 3193.

  25. L. S. Liu, F. Wang, Y. Ge, P. K. Lo.* “ Recent Developments in Aptasensors for Diagnostic Applications” ACS Applied Materials & Interfaces, 2021, 13, 8, 9329–9358.

  26. D. Y. Tam, J. W.-T Ho, M. S. Chan, C. H. Lau, T. J. H. Chang, H. M. Leung, L. S. Liu, F. Wang, L. L. H. Chan, C. Tin, P. K. Lo.* “Penetrating the Blood–Brain Barrier by Self-Assembled 3D DNA Nanocages as Drug Delivery Vehicles for Brain Cancer Therapy” ACS Applied Materials & Interfaces, 2020, 12, 26, 28928−28940.

  27. M. S. Chan, H. M. Leung, S. W. Wong, Z. Lin, Q. Gao, T. J. H. Chang, K. W. C. Lai, P. K. Lo.* “Reversible Reconfiguration of Well-Defined High-Order DNA Nanostructures by G-Quadruplex-Mediated Assembly Approach” Nanoscale, 2020, 12, 4, 2464-2471.

  28. Q. Gao, Z. Dai, S. Zhang, Y. Fang, K. Yung, P. K. Lo,* K. W. C. Lai.* “Interaction of Sp1 and APP promoter elucidates a mechanism for Pb2+ caused neurodegeneration”. Archives of Biochemistry and Biophysics, 2020, 681, 108265.

  29. L. T. Chu, H. M. Leung, P. K. Lo, T. H. Chen.* “Visual Detection of Lead Ions Based on Nanoparticle-Amplified Magnetophoresis and Mie Scattering” Sensors and Actuators B- Chemical 2020, 306, 127564.

  30. F. Wang, H. Chen, Z. Liu, F. Mi, X. Fang, J. Liu, M. Wang, P. K. Lo, Q, Li.* “Conjugated polymer dots for biocompatible siRNA delivery” New J. Chem., 2019, 43, 36, 14443-14449.

  31. F. Wang, L. S. Liu, C. H. Lau, T. J. H. Chang, D. Y. Tam, H. M. Leung, C. Tin, P. K. Lo.* “Synthetic α-L-Threose Nucleic Acids Targeting BcL-2 Show Gene Silencing and in Vivo Antitumor Activity for Cancer Therapy” ACS Applied Materials & Interfaces 2019, 11, 38510-38518.

  32. L. Wei, H. M. Leung, Y. Tian, P. K. Lo, D. Ho.* “Fully-Integrated Liquid-core Waveguide Fluorescence Lifetime Detection Microsystem for DNA Biosensing” IEEE Access 2019, 7, 111944-111953.

  33. C. H. Lau, J. W. T. Ho, P. K. Lo, C. Tin.* “Targeted Transgene Activation in the Brain Tissue by Systemic Delivery of Engineered AAV1 Expressing CRISPRa” Molecular Therapy - Nucleic Acids 2019, 16, 637-649.

  34. M. S. Chan, R. Landig, J. Choi, H. Zhou, X. Liao, M. D. Lukin, H. Park, P. K. Lo.* “Stepwise Ligand-Induced Self-Assembly for Facile Fabrication of Nanodiamond-Gold Nanoparticle Dimers via Non-Covalent Biotin-Streptavidin Interactions” Nano Lett. 2019 19, 3, 2020-2026.

  35. D. Y. Tam, X. Zhuang, S. W. Wong, P. K. Lo.* “Photo-Responsive Self-Assembled DNA Nanomaterials: Design, Working Principles and Applications” Small 2019, 15, 26, 1805481.

  36. Q. Gao, Z. Dai, Y. Fang, P. K. Lo, K. W. C. Lai.* “Identification of Energy Landscape of Sp1 Zinc-Finger in Pb(II) or Cd(II) Using AFM” Applied Physics Letters 2019, 114, 1, 013701.

  37. C. Liu, B. Zhou, Y. Geng, D. Y. Tam, R. Feng, H. Miao, N. Xu, X. Shi, Y. You, Y. Hong, B. Z. Tang, P. K. Lo, V. Kuryavyi,* G. Zhu.* “A Chair-type G-quadruplex Structure Formed by a Human Telomeric Variant DNA in K+ Solution” Chem. Sci., 2019, 10, 1, 218–226.

  38. Z. Dai, H. M. Leung, Q. Gao, F. Wang, S. W. Wong, L. S. Liu, Y. J. Au, K. W. C. Lai,* P. K. Lo.* “Facile Construction of DNA Tetrahedron in Unconventional Ladder-Like Arrangements at Room Temperature” Nanoscale Adv. 2019, 1, 3, 1240-1248.

  39. H. M. Leung, M. S. Chan, L. S. Liu, S. W. Wong, T. W. Lo, C. H, Lau, C. Tin, P. K. Lo.* “Dual-Function, Cationic Peptide-Coated Nanodiamond Systems: Facilitating Nuclear-Targeting Delivery for Enhanced Gene Therapy Applications” ACS Sustainable Chemistry & Engineering 2018, 6, 8, 9671–9681.

  40. L. S. Liu, H. M. Leung, D. Y. Tam, T. W. Lo, S. W. Wong, P. K. Lo.* “α-L-Threose Nucleic Acids as Biocompatible Antisense Oligonucleotides for Suppressing Gene Expression in Living Cells” ACS Applied Materials & Interfaces 2018, 10, 11, 9736-9743.

  41. Z. Dai, P. K. Lo.* “Photo-Switchable Patterning of Gold Nanoparticles Along 3D DNA Nanotubes” Nanoscale 2018, 10, 12, 5431-5435.

  42. D. Y. Tam, H. M. Leung, M. S. Chan, P. K. Lo.* “G-Quadruplex-Mediated Molecular Switching of Self-Assembled 3D DNA Nanocages” ChemNanoMat 2017, 3, 10, 750-754.

  43. G. Wu, Z. Dai, X. Tang, Z. Lin, P. K. Lo,* M. Meryyappan,* K. W. C. Lai.* “Graphene Field-Effect Transistors for the Sensitive and Selective Detection of Escherichia Coli Using Pyrene-Tagged DNA Aptamer” Advanced Healthcare Materials, 2017, 6, 19, 1700736.

  44. M. S. Chan, H. M. Leung, L. S. Liu, P. K. Lo.* “Cancer-Cell-Specific Mitochondria-Targeted Drug Delivery by Dual-Ligand-Functionalized Nanodiamonds Circumvents Drug Resistance” ACS Applied Materials & Interfaces 2017, 9, 7, 11780-11789.

  45. R.Chen, J. Zhang, J. Chelora, Y. Xiong, S. Kershaw, K. F. Li, P. K. Lo, K. W. Cheah, A. L. Rogach, J. A. Zapien, C. S. Lee.* “Ruthenium (II) Complex Incorporated UiO-67 Metal-Organic Frameworks Nanoparticles for Enhanced Two-Photon Fluorescence Imaging and Photodynamic Cancer Therapy” ACS Applied Materials & Interfaces 2017, 9, 11780-11789.

  46. Z. Dai, H. M. Leung, P. K. Lo.* “Stimuli-Responsive Self-Assembled DNA Nanomaterials for Biomedical Applications” Small 2017, 13, 7, 1602881.

  47. Z. Dai, Q. Gao, M. C. Cheung, H. M. Leung, T. C. K. Lau, H. F. Sleiman, K. W. C. Lai,* P. K. Lo.* “A Highly Versatile Platform Based on Geometrically Well-Defined 3D DNA Nanostructures for Selective Recognition and Positioning of Multiplex Targets” Nanoscale 2016, 8, 46, 18291-18295.

  48. M. S. Chan, D. Y. Tam, Z. Dai, L. S. Liu, J. W. Ho, M. L. Chan, D. Xu, M. S. Wong, C. Tin,* P. K. Lo.* “Mitochondrial Delivery of Therapeutic Agents By Amphiphilic DNA Nanocarriers” Small 2016, 12, 6, 770-781.

  49. W. Liu, L. Liang, P. K. Lo, X. J. Gou, X. H. Sun. “A Double Branched Photosensitive Prodrug: Synthesis and Characterization of Light Triggered Drug Release” Tetrahedron Lett. 2016, 57, 8, 959-963.

  50. Z. Wang, D. Y. Tam, A. S. Susha, M. S. Chan, S. V. Kershaw, P. K. Lo, A. L. Rogach. “Aggregation-Free DNA Nanocages/Quantum Dot Complexes Based on Electrostatic Adsorption” Colloid Surf. A-Physicochem. Eng. Asp. 2016, 495, 62-67.

  51. D. Y. Tam, Z. Dai, M. S. Chan, L. S. Liu, M. C. Cheung, F. Bolze, C. Tin, P. K. Lo.* “A Reversible DNA Logic Gate Platform Operated by One- and Two-Photon Excitations” Angew. Chem.-Int. Edit. 2016, 55, 1, 164-168.

  52. S. Chen., L. T. Chu, P. P. Yeung, Z. Zhao, Y. Bao, M. S. Chan, P. K. Lo, T. H. Chen.* “Enzyme-Free Amplification by Nano Sticky Balls for Visual Detection of ssDNA/RNA Oligonucleotides” ACS Applied Materials & Interfaces 2015, 7, 41, 22821-22830.

  53. M. S. Chan, D. Xu, L. Guo, D. Y. Tam, L. S. Liu, Y. Chen, M. S. Wong,* P. K. Lo.* “Cyanine Fluorophore for Cellular Protection Against ROS in Stimulated Macrophages and Two-Photon ROS Detection” Org. Biomol. Chem., 2015, 13, 26, 7307-7312.

  54. Z. Dai, D. Y. Tam, H. Xu, M. S. Chan, L. S. Liu, F, Bolze,* X. H. Sun, P. K. Lo.* “Conformational Change of Self-Assembled DNA Nanotubes Induced by Two-Photon Excitation” Small 2015, 11, 33, 4090-4096.

  55. L. Guo, M. S. Chan, D, Xu, D. Y. Tam, F. Bolze, P. K. Lo,* M. S. Wong.* “Indole-based Cyanines as a Nuclear RNA-Selective Two-Photon Fluorescent Probe for Live Cell Imaging”. ACS Chem. Bio. 2015, 10, 5, 1171-1175.

  56. D. Y. Tam, P. K. Lo.* “Multifunctional DNA Nanomaterials for Biomedical Applications”. J. Nanomater. Vol. 2015, Article ID 765492, 21 pages, 2015.

  57. O. Sushkov, N. Chisholm, I. Lovchinsky, M. Kubo, P. K. Lo, S. D. Bennett, D. Hunger, A. Akimov, R. L. Walsworth, H. Park,* M. D. Lukin.* “All-Optical Sensing of a Single-Molecule Electron Spin”. Nano Lett. 2014, 14, 11, 6443-6448.

  58. M. S. Chan, P. K. Lo.* “Nanoneedle-Assisted Delivery of Site-Selective Peptide-Functionalized DNA Nanocages for Mitochondria and Nucleus Targeting” Small 2014, 10, 7, 1255-1260.

  59. D. Liu, C. Yi, K. Wang, C. C. Fong, Z. Wang, P. K. Lo, D. Sun, M. S. Yang. “Reorganization of Cytoskeleton and Transient Activation of Ca2+ Channels in Mesenchymal Stem Cells Cultured on Silicon Nanowire Arrays” ACS Applied Materials & Interfaces 2013, 5, 24, 13295-13304.

  60. G. Kucsko, P. C. Maurer, N. Y. Yao, M. Kubo, H. J. Noh, P. K. Lo, H. Park,* and M. D. Lukin.* “Nanometer- Scale Thermometry in a Living Cell” Nature 2013, 500, 7460, 54-59.

  61. W. Yang, P. S. Chan, M. S. Chan, K. F. Li, P. K. Lo, N. K. Mak, K. W. Cheah, M. S. Wong.* “Two-Photon Fluorescence Probes for Imaging of Mitochondria and Lysosomes” Chem. Commun. 2013, 49, 33, 3428-3430.

  62. D. R. Glenn, H. Zhang, N. Kasthuri, R. Schalek, P. K. Lo, A. S. Trifonov, H. Park, J. W. Lichtman, R. L. Walsworth.* “Correlative Light and Electron Microscopy Using Cathodoluminescence from Nanoparticles with Distinguishable Colors” Scientific Reports, 2012, 2, 865.

  63. W. Yang, Y. Chen, M. S. Wong,* P. K. Lo.* “Reinforced Self-assembly of Donor-Acceptor π-Conjugated Molecules to DNA Templates by Dipole-Dipole Interactions Together with Complementary Hydrogen Bonding Interactions for Biomimetics” Biomacromolecules 2012, 13, 10, 3370-3376.

Publications before CityU

  1. C. K. Ho, S. Y. Poon, P. K. Lo, M. S. Wong, W. Y. Wong. “Synthesis, Characterization and Photophysical Properties of Metallopolyynes and Metallodiynes of Platinum(II) with Dibenzothiophene Derivatives”. Journal of Inorganic and Organometallic Polymers and Materials 2013, 23, 206-215.

  2. H. Yan, A. Florian, D. A. deBruijn, C. K. McLaughlin, P. K. Lo, H. F. Sleiman.* “Chiral Metal-DNA Four-Arm Junctions and Metalated Nanotubular Structures” Angew. Chem.-Int. Edit. 2011, 50, 20, 4620-4623.

  3. P. K. Lo, P. Karam, F. A. Aldaye, C. K. McLaughlin, G. Hamblin, G. Cosa, H. F. Sleiman.* “Loading and Selective Release of Cargo in DNA Nanotubes with Longitudinal Variation” Nat. Chem. 2010, 2, 4, 319-328.

  4. P. K. Lo, K. Metera, H. F. Sleiman.* “Self-Assembly of Three-Dimensional DNA Nanostructures and Potential Biological Applications” Current Opinion in Chemical Biology 2010, 14, 5, 597-607.

  5. P. K. Lo, F. Altvater, H. F. Sleiman.* “Templated Synthesis of DNA Nanotubes with Controlled, Predetermined Lengths” J. Am. Chem. Soc. 2010, 132, 30, 10212-10214.

  6. Y. Wen, C. K. McLaughlin, P. K. Lo, H. Yang, H. F. Sleiman.* “Stable Gold Nanoparticle Conjugation to Internal DNA Positions: Facile Generation of Discrete Gold Nanoparticle-DNA Assemblies” Bioconjugate Chem. 2010, 21, 8, 1413-1416.

  7. P. K. Lo, H. F. Sleiman.* “Templated Polymerization of Conjugated Polymers” Synfacts 2009, 06, 0621-0621.

  8. P. K. Lo, H. F. Sleiman.* “Nucleobase-Templated Polymerization: Copying the Chain Length and Polydispersity of Living Polymers into Conjugated Polymers” J. Am. Chem. Soc. 2009, 131, 12, 4182-4183.

  9. F. A. Aldaye, P. K. Lo, P. Karam, C. K. McLaughlin, G. Cosa, H. F. Sleiman.* “Modular Construction of DNA Nanotubes with Readily Tunable Geometry, Rigidity, and Single- or Double-Stranded Character” Nat. Nanotech. 2009, 4, 6, 349-352.

  10. P. K. Lo, F. A. Aldaye, H. F. Sleiman.* “Modular Construction of DNA Nanotubes of Tunable Geometry, Alternating Size, and Single- or Double-Stranded Character” Journal of Biomolecular Structure & Dynamics 2009, 26, 6, 801.

  11. Z. Q. Gao,* P. F. Xia, P. K. Lo, B. X. Mi, H. L. Tam, M. S. Wong,* K. W. Cheah, C. H. Chen. “p-Doped p-Phenylenediamine-Substituted Fluorenes for Organic Electroluminescent Devices” Organic Electronics 2009, 10, 4, 666-673.

  12. P. K. Lo, H. F. Sleiman.* “Synthesis and Molecular Recognition of a Conjugated Polymer with DNA-Mimetic Properties” Macromolecules 2008, 41, 15, 5590-5603.

  13. P. K. Lo, M. S. Wong.* “Extended Calix[4]arene-Based Receptors for Molecular Recognition and Sensing” Sensors 2008, 8, 9, 5313-5335.

  14. P. K. Lo, K. F. Li, M. S. Wong,* K.W. Cheah.* “Synthesis and Structure-Linear and Structure-Nonlinear Optical Properties of Multi-Dipolar Zigzag Oligoaryleneethynylenes” J. Org. Chem. 2007, 72, 18, 6672-6629.

  15. P. K. Lo, D. Z. Chen, Q. W. Meng,* M. S. Wong.* “Highly Ordered Smectic Phases from Polar Calix[4]arene Derivatives” Chem. Mater. 2006, 18, 17, 3924-3930.

  16. J. Lu, P. F. Xia, P. K. Lo, Y. Tao,* M. S. Wong.* “Synthesis and Properties of Multi-Triarylamine-Substituted Carbazole-Based Dendrimers with an Oligothiophene Core for Potential Applications in Organic Solar Cells and Light-Emitting Diodes”. Chem. Mater., 2006, 18, 26, 6194-6203.

  17. M. S. Wong,* P. F. Xia, P. K. Lo, X. H. Sun, W. Y. Wong,* S. M. Shuang*. “Synthesis of Oligophenylene-Substituted Calix[4]crown-4s and Their Silver(I) Ion-Induced Nanocones Formation” J. Org. Chem. 2006, 71, 3, 940-946.

  18. M. S. Wong,* P. F. Xia, X. L. Zhang, P. K. Lo, Y, -K, Cheng, K. -K. Yeung, X. Guo, S. M. Shuang. “Facile Synthesis of Oligophenylene-Substituted Calix[4]arenes and Their Enhanced Binging Properties”. J. Org. Chem, 2005, 70, 7, 2816-2819.

Patents

  1. Design and Synthesis of π-Extended Photocleavable Protecting Groups for Highly Efficient Two-Photon Uncaging of Functional Nucleic Acids
    LO, P. K. P., CHANG, T. J. H., ZHOU, Z. PWG/PA/2360/4/2026 US Non-Provisional Patent Application

  2. Nuclease-Resistant Xeno-Nucleic Acid Hairpin Probes For Isothermal Signal Amplification In Biological Matrices/ 用于生物基质中等温信号放大的抗核酸酶异源核酸发夹探针
    LO, P. K. P., LI, P., LI, X., ZHOU, Z. 15 May 2026, (Accepted/In press/Filed) Priority of U.S. Patent Application No. 19/678,187; China Invention Patent Application No. 202611149798.5

  3. A Biomimetic Drug Delivery System By TNA Technology For Triple Negative Breast Cancer Therapy
    LO, P. K. P., ZHENG, W., CHANG, T. J. H. 4 February 2026, (Accepted/In press/Filed) Priority of U.S. Patent Application No. 63/975,357

  4. Enrofloxacin Specific Aptamers And Uses Thereof
    KWOK, C. K., LO, P. K. P., LAM, S. Y. & LI, P., 27 March 2026, (Accepted/In press/Filed) Priority of U.S. Patent Application No. 19/631,896

  5. Methods And Compositions for Synthesis of Two-photon Cleavable Phosphoramidite Molecules for Oligonucleotide Conjugation
    LO, P. K. P., LIU, L. S. & TAM, D. Y., 26 Mar 2024, Patent No. US11,938,187, Priority of U.S. Patent Application No. 17/344,920

  6. Graphene Oxide-Based Fluorescent Sensor For Biomolecule Detection
    LO, P. K. P., LI, P., LIU, L. S. & WANG, F., LEUNG, H. M., 11 April 2024, (Accepted/In press/Filed) Priority of U.S. Patent Application No. 18/632,333

  7. TNA-Based Probe For Detecting And Imaging A Target miRNA In Living Cells
    LO, P. K. P., WANG, F. & LIU, L. S., 5 Sept 2022, (Accepted/In press/Filed) Priority of U.S. Patent Application No. 63/256,640

P.K. Peggy LO @ 2022                  City University of Hong Kong       Department of Chemistry       College of Science