(PI and Co-I represent principal investigator and co-investigator, respectively.)
Health and Medical Research Fund (HMRF)
Development of Light-Responsive Nanocarriers as Controlled Drug Release Platform for Triple-Negative Breast Cancer Therapy. PI, 2022 –2025.
NIP7 as a Novel Therapeutic Target For Triple-Negative Breast Cancer. Co-I (10 % of the research project), 2022 –2025.
Development of a New Class of Targeted Therapeutics for Triple-Negative Breast Cancer Therapy. PI, 2020 –2023.
Overcoming Blood-Brain Barrier to Treat Brain Cancers by Multifunctional Nanodiamond-Mediated Drug Delivery System. PI, 2018 –2020.
Design and Development of Multifunctional 3D DNA Nanostructures as Brain-Targeted Drug Nanocarriers for Treatment of Brain Diseases. PI, 2016 –2018.
Development and Targeted-Specificity Profiling of Highly Fluorescent DNA-Mimetic Polymers as Therapeutic Agents for Gene Silencing. PI, 2015 –2017.
General Research Fund (GRF/ECS)
Design, Synthesis and Characterization of Multi-Functionalized Two-Photon Caging Platforms and Their Application to Neurotransmitter Photorelease. PI, 2022 –2024.
Design, Synthesis and Applications of Two-Photon Photoactivatable Nucleic Acids in DNA Nanotechnology. PI, 2021 –2023.
Design, Assembly and Operations of a Series of Photochemically Controlled DNA Logic Devices. PI, 2020 –2022.
Design, Assembly, Characterization and Biological Applications of Biocompatible and Multifunctional 3D DNA Nanocages in Living Cells. PI, 2015 –2017.
National Natural Science Foundation of China Grants (NSFC)
Development of Nanodiamond-Based Thermal Sensor for Monitoring of Health Status of Living Cells. PI, 2018 –2021.
Two-Photon Induced Conformational Changes of DNA Nanostructures and Their Potential Application in Controlled Release of Encapsulated Cargos. PI, 2016 –2019.
Targeted Delivery of Drug-Loaded DNA Nanocages to Mitochondria in Living Cells for Cancer Therapy. PI, 2014 –2016